Researchers have uncovered new details about the molecular workings of Obstructive Sleep Apnea (OSA) using a mouse model. It was revealed that the motor neurons in the face and jaws of animals with OSA showed swollen endoplasmic reticula, a protein network where cellular proteins are made. The cause for the above phenomena was attributed to a build-up of poorly folded proteins, which develop when exposed to oxygen fluctuations over a period of time.

J Neurosci 2008 feb 27; 28 (9); 2168-78

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