According to a recent study by Toronto researchers, which involved hamsters whose circadian clocks were disrupted by mutations to be out-of-sync with the environment, it was found that these animals were more likely than normal hamsters to develop heart and kidney disease, extensive fibrosis and other health issues. They also found that once the animals circadian clocks were normalized these effects were reversed. The results suggest that circadian rhythm disruptions such as jet lag and shift work are associated with serious health problems and that circadian organization is vital for good health and longevity.

Am J physiol Regul Integr comp Physiol 2008 Jul: 951(1) R 369

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