A new study of Rhesus monkeys who were deprived of sleep for 30-36 hrs, were administered Orexin intravenously or via nasal spray. Researchers found that both nasal and Intravenous Orexin improved the monkey’s performance on the test, and that the nasal spray was more effective than intravenous Orexin. This shows that a nasal spray containing Orexin (a naturally occurring chemical in the brain) can increase attention, alertness and reduce low performance associated with sleep deprivation.

The Journal of Neuroscience, Dec.26, 2007, 27(52):14239-14247

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